Los Angeles Chargers host Arizona Cardinals in Week 1 of the 2026 NFL season at SoFi Stadium on Monday. Read on for our full match preview, betting tips, and best odds.
Mike McDaniel is now the Chargers’ offensive coordinator, and it’s an exciting new-look offense as a result but in classic Chargers fashion they’ve lost a lineman for the season in Tyler Biadasz but Alt &Slater are good to go.
Arizona have surprisingly named rookie Jeremiah Love as their RB2, more fantasy-relevant than anything else. I would have a higher opinion of the Cards if they were starting Carson Beck over Jacoby Brissett given how Beck performed and led in the preseason and his college experience. I’ve also got genuine concerns about Marvin Harrison Jr.’s ceiling if the quarterback situation doesn’t sort itself out.
Herbert’s got his own prove-it narrative, still without a playoff win despite all the draft hype and this McDaniel offence could blow the doors off a stuttering Arizona.
Los Angeles Chargers vs Arizona Cardinals Odds & Popular Betting Markets
Here’s a quick look at the current odds and popular betting markets for the Los Angeles Chargers vs Arizona Cardinals matchup.
*odds are correct at the time of publishing and are subject to change
| Team | Odds | |
|---|---|---|
| Arizona Cardinals (9.5) | 1.87 | Bet Now |
| Los Angeles Chargers (-9.5) | 1.90 | Bet Now |
NFL odds correct as of 11/09/2026 and subject to change. Event scheduled to start at 14/09/2026 6:25am AEST.
NFL odds correct as of 11/09/2026 and subject to change. Event scheduled to start at 14/09/2026 6:25am AEST.